☣️ UN 2378 • CLASS 3
UN 2378 — 2-Dimethylaminoacetonitrile
Placard: Flammable. ERG Guide 131. Training/quick-reference only — use current ERG + SOP/SOG for incident-specific actions.
🚒☣️
⚠️ This page is a quick-reference aid. For real incidents: stage upwind, isolate, deny entry, request Hazmat early, and consult the current ERG + SOP/SOG.
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UN 2378 Quick Details
UN 2378
Product name: 2-Dimethylaminoacetonitrile
DOT Class: 3
Placard type: Flammable
ERG Guide: 131 (check current ERG)
Initial isolation: ERG 131: Isolate spill 50m all directions; if tank/rail car involved in fire, isolate 800m and consider evacuation 1600m downwind
Common Hazards of UN 2378
- TOXIC; may be fatal if inhaled, ingested or absorbed through skin.
- Inhalation or contact with some of these materials will irritate or burn skin and eyes.
- Methyl chloroacetate (UN2295) is an eye irritant/lachrymator (causes flow of tears).
- Fire will produce irritating, corrosive and/or toxic gases.
- Vapors may cause dizziness or asphyxiation, especially when in closed or confined areas.
- Runoff from fire control or dilution water may cause environmental contamination.
- HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
- Vapors may form explosive mixtures with air.
Chemical Identity & Physical Properties
| Also known as | DimethylaminoacetonitrileDMANN,N-Dimethylglycine nitrileDimethylglyconitrile2-(Dimethylamino)acetonitrile |
| CAS Number | 926-64-7 |
| Appearance | Colorless to pale yellow liquid with an amine-like or fishy odor. Volatile and miscible with water. |
| Flash Point | 41°C (106°F) |
| Boiling Point | 135-137°C (275-279°F) |
| Vapor Density | 2.9 (heavier than air) |
| Water Reactivity | Soluble in water; no violent reaction but may hydrolyze slowly releasing cyanide |
Chemical details are general reference only. Always verify with current SDS, ERG, and SOP/SOG.
Fireground Response Guidance — UN 2378
Extinguishing Media
Alcohol-resistant foam, CO2, dry chemical powder; water spray for cooling only
PPE Requirements
⚠️ Level A or B required; SCBA mandatory; butyl rubber or nitrile gloves; full chemical protective suit due to severe skin absorption hazard
Isolation & Evacuation
ERG 131: Isolate spill 50m all directions; if tank/rail car involved in fire, isolate 800m and consider evacuation 1600m downwind
Always confirm protective actions with the current edition of the Emergency Response Guidebook (ERG Guide 131).
First Actions for a UN 2378 Incident
- CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper
- Keep unauthorized personnel away.
- Stay upwind, uphill and/or upstream.
- Ventilate closed spaces before entering, but only if properly trained and equipped.
- Isolate spill or leak area for at least 50 meters (150 feet) in all directions.
- For highlighted materials: see Table 1 - Initial Isolation and Protective Action Distances.
- For non-highlighted materials: increase the immediate precautionary measure distance, in the downwind
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📋 Copy & Share Field Card
UN 2378 — 2-DimethylaminoacetonitrileHAZMAT RADIO NOTE — UN 2378
Product: 2-Dimethylaminoacetonitrile
Class 3 / Flammable / ERG 131
PPE: Level A or B required; SCBA mandatory; butyl rubber or nitrile gloves; full chemical protective suit due to severe skin absorption hazard
ISOLATION: ERG 131: Isolate spill 50m all directions; if tank/rail car involved in fire, isolate 800m and consider evacuation 1600m downwind
ACTION: Stage upwind · Isolate · Deny entry · Request HazmatRADIO
Use for: Quick radio or face-to-face size-up. Short, structured, field-ready.
=== IC HAZMAT BRIEFING ===
UN 2378 — 2-Dimethylaminoacetonitrile
Class: 3 | Placard: Flammable | ERG Guide: 131
Appearance: Colorless to pale yellow liquid with an amine-like or fishy odor. Volatile and miscible with water.
Water Reactivity: Soluble in water; no violent reaction but may hydrolyze slowly releasing cyanide
Extinguishing: Alcohol-resistant foam, CO2, dry chemical powder; water spray for cooling only
PPE: Level A or B required; SCBA mandatory; butyl rubber or nitrile gloves; full chemical protective suit due to severe skin absorption hazard
Isolation: ERG 131: Isolate spill 50m all directions; if tank/rail car involved in fire, isolate 800m and consider evacuation 1600m downwind
— Key Hazards —
• TOXIC; may be fatal if inhaled, ingested or absorbed through skin.
• Inhalation or contact with some of these materials will irritate or burn skin and eyes.
• Methyl chloroacetate (UN2295) is an eye irritant/lachrymator (causes flow of tears).
— First Actions —
• CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper
• Keep unauthorized personnel away.
• Stay upwind, uphill and/or upstream.
• Ventilate closed spaces before entering, but only if properly trained and equipped.
SOURCE: allfirefighter.com/hazmat/un/2378 | Always use current ERG + SOP/SOGIC BRIEFING
Use for: Incident command briefing, staging area whiteboard, or pre-entry team brief. Full chemical + response details.
UN2378 2-Dimethylaminoacetonitrile Cls3 ERG131 | allfirefighter.com/hazmat/un/2378SMS / 160 CHAR
Use for: Quick text to command or incoming units. Fits in a single SMS. Includes link to full page.
⚠️ Quick-reference only. Always use current ERG + SOP/SOG for incident-specific actions.
Page: https://allfirefighter.com/hazmat/un/2378
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Frequently Asked Questions about UN 2378
TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Methyl chloroacetate (UN2295) is an eye irritant/lachrymator (causes flow of tears). Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or asphyxiation, especially when in closed or confined areas. Runoff from fire control or dilution water may cause environmental contamination. HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air.
CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper Keep unauthorized personnel away. Stay upwind, uphill and/or upstream.
Level A or B required; SCBA mandatory; butyl rubber or nitrile gloves; full chemical protective suit due to severe skin absorption hazard
Water reactivity: Soluble in water; no violent reaction but may hydrolyze slowly releasing cyanide. Recommended extinguishing: Alcohol-resistant foam, CO2, dry chemical powder; water spray for cooling only.
ERG Guide 131 recommendation: ERG 131: Isolate spill 50m all directions; if tank/rail car involved in fire, isolate 800m and consider evacuation 1600m downwind
No. This is a training/quick-reference aid only. Always consult the current ERG Guide 131 and your department SOP/SOG for incident-specific protective actions.
Sources (high level): DOT/PHMSA marking & class concepts + ERG usage principles.
This page does not reproduce ERG guide text—always consult the current ERG for incident-specific protective actions.